2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

Base Information

Chemical Name:2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide
CAS No.:1610623-82-9
Molecular Formula:C₃₀H₂₈BrN₃O₂
Molecular Weight:542.475
Hs Code.:

Synonyms:2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

Suppliers and Price of 2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

There total 2 articles about 2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1610623-72-7
C₃₀H₂₉Br₂N₃O₂

: 1610623-82-9
2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

Guidance literature:: With palladium diacetate; potassium carbonate; triphenylphosphine; In toluene; Reflux;
DOI:10.1016/j.tet.2014.03.079

Reference yield:

Indole-2-carboxylic acid: 1477-50-5,1228050-17-6
Indole-2-carboxylic acid

: 931-53-3
Cyclohexyl isocyanide

2-bromo-p-toluidine: 583-68-6
2-bromo-p-toluidine

: 1122-91-4
4-bromo-benzaldehyde

: 1610623-82-9
2-(4-bromophenyl)-N-cyclohexyl-2-(2-methyl-6-oxo-6,7-dihydro-5H-indolo[2,3-c]quinolin-5-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 24 h / 20 °C

2: palladium diacetate; triphenylphosphine; potassium carbonate / toluene / Reflux

With palladium diacetate; potassium carbonate; triphenylphosphine; In methanol; toluene; 1: |Ugi Condensation;
DOI:10.1016/j.tet.2014.03.079