N-(2-Methylbenzoxazol-6-yl)-N'-(1,5-naphthyridin-4-yl)urea hydrochloride

Base Information

• Chemical Name: N-(2-Methylbenzoxazol-6-yl)-N'-(1,5-naphthyridin-4-yl)urea hydrochloride
• CAS No.: 249889-64-3
• Molecular Formula: C17H13 N5 O2 . Cl H
• Molecular Weight: 354.796
• DSSTox Substance ID: DTXSID10947856
• Pharos Ligand ID: SFAKCCYCZKA1
• ChEMBL ID: CHEMBL2111553
• Mol file: 249889-64-3.mol

Synonyms:1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea;1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea hydrochloride;SB 334867-A;SB 334867A;SB-334867;SB-334867-A;SB-334867A;SB334867A

Chemical Property of N-(2-Methylbenzoxazol-6-yl)-N'-(1,5-naphthyridin-4-yl)urea hydrochloride

Chemical Property:

• Vapor Pressure: 2.63E-08mmHg at 25°C
• Refractive Index: 1.793
• Boiling Point: 450.5°C at 760 mmHg
• Flash Point: 226.2°C
• PSA: 92.94000
• Density: 1.472g/cm³
• LogP: 3.86940
• Storage Temp.: Desiccate at RT
• Solubility.: Dichloromethane (Slightly), DMSO (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 355.0836024
• Heavy Atom Count: 25
• Complexity: 462

Purity/Quality:

99% ^*data from raw suppliers

SB334867 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4.Cl
• Uses: SB 334867 is an orexin-1-receptor antagonist. An important ligand for the study of the orexin 1 (OX1) receptor due to its high OX1/OX2 selectivity and bioavailability.

Technology Process of N-(2-Methylbenzoxazol-6-yl)-N'-(1,5-naphthyridin-4-yl)urea hydrochloride

There total 1 articles about N-(2-Methylbenzoxazol-6-yl)-N'-(1,5-naphthyridin-4-yl)urea hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-methylbenzoxazole-6-yl)-3-[1,5]naphthyridine-4-yl urea → 1-(2-methylbenzoxazole-6-yl)-3-[1,5]naphthyridine-4-yl urea hydrochloride (249889-64-3)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 0 - 60 ℃;

Refernces