dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol

Base Information

• Chemical Name: dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol
• CAS No.: 113007-91-3
• Molecular Formula: C₁₃H₁₇NO₃S
• Molecular Weight: 267.349
• Mol file: 113007-91-3.mol

Synonyms:dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol

Chemical Property of dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol

There total 6 articles about dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol triphenylmethyl ether (113007-90-2) → dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol (113007-91-3)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; methanol; at 45 ℃; for 2h;

DOI:10.1021/jm00163a038

Reference yield:

1-hydroxy-2-(2-hydroxyethyl)cyclopent-3-ene (49826-08-6,54483-54-4,54483-55-5,75331-67-8) → dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol (113007-91-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 96 percent / Et₃N, 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

3: NaN₃ / dimethylformamide / 5 h / 75 °C

4: 1.) Ph₃P, 2.) H₂O / 1.) RT, 15 h, 2.) a.) 45 deg C, 2 h, b.) reflux, 1 h

5: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

6: 99 percent / 1 N aq. HCl / tetrahydrofuran; methanol / 2 h / 45 °C

With hydrogenchloride; dmap; sodium azide; water; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00163a038

Reference yield:

dl-trans-2-(2-aminocyclopent-4-enyl)ethanol triphenylmethyl ether (113007-89-9) → dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol (113007-91-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

2: 99 percent / 1 N aq. HCl / tetrahydrofuran; methanol / 2 h / 45 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1021/jm00163a038

upstream raw materials:

dl-trans-2-<2-<(phenylsulfonyl)amino>cyclopent-4-enyl>ethanol triphenylmethyl ether

1-hydroxy-2-(2-hydroxyethyl)cyclopent-3-ene

dl-trans-2-(2-aminocyclopent-4-enyl)ethanol triphenylmethyl ether

dl-cis-2-(2-hydroxycyclopent-4-enyl)ethanol triphenylmethyl ether

Downstream raw materials:

dl-(1β,2α,3β,5β)-2-(formylmethyl)-3-<(phenylsulfonyl)amino>-6-oxabicyclo<3.1.0>hexane

dl-(1α,2α,3β,5α)-2-(formylmethyl)-3-<(phenylsulfonyl)amino>-6-oxabicyclo<3.1.0>hexane

dl-(1β,2α,3β,5β)-7-<3-<(phenylsulfonyl)amino>-6-oxabicyclo<3.1.0>hex-2-yl>-5(Z)-heptenoic acid

dl-(1α,2α,3β,5α)-7-<3-<(phenylsulfonyl)amino>-6-oxabicyclo<3.1.0>hex-2-yl>-5(Z)-heptenoic acid