Technology Process of N-(2-(trifluoromethyl)phenyl)cianamide
There total 4 articles about N-(2-(trifluoromethyl)phenyl)cianamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
fluorosulfonyl fluoride; triethylamine;
In
dichloromethane;
at 20 ℃;
for 2h;
Schlenk technique;
DOI:10.1039/c9ob01547g
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydroxylamine / water; ethanol / 3 h / Reflux
2: fluorosulfonyl fluoride; triethylamine / dichloromethane / 2 h / 20 °C / Schlenk technique
With
fluorosulfonyl fluoride; hydroxylamine; triethylamine;
In
ethanol; dichloromethane; water;
2: |Tiemann Rearrangement;
DOI:10.1039/c9ob01547g
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hydroxylamine / acetonitrile / 2 h / Reflux
2: triethylamine; fluorosulfonyl fluoride / acetonitrile / 0.5 h / 20 °C
3: hydroxylamine / acetonitrile / 3 h / Reflux
4: triethylamine; fluorosulfonyl fluoride / dichloromethane / 2 h / 20 °C
With
fluorosulfonyl fluoride; hydroxylamine; triethylamine;
In
dichloromethane; acetonitrile;
DOI:10.1039/d0ra02631j
