Technology Process of C23H18ClN7O
There total 8 articles about C23H18ClN7O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium hydroxide;
In
1,4-dioxane; water;
Sealed tube;
Heating;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 2.08 h / 20 °C
1.2: 2 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -30 - -10 °C / Inert atmosphere
2.2: 2 h / -50 - -10 °C / Inert atmosphere
3.1: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 72 h / 60 °C
4.1: ammonium hydroxide / water; 1,4-dioxane / Sealed tube; Heating
With
ammonium hydroxide; n-butyllithium; oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide;
In
tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride / water; isopropyl alcohol / 3 h / 65 °C
2: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 72 h / 60 °C
3: ammonium hydroxide / water; 1,4-dioxane / Sealed tube; Heating
With
hydrogenchloride; ammonium hydroxide; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; water; isopropyl alcohol;