Technology Process of C16H14N2O
There total 4 articles about C16H14N2O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
chloroform;
at 20 ℃;
for 1h;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: thionyl chloride; N,N-dimethyl-formamide / 16 h / 20 °C / Cooling with ice
2.1: pyridinium p-toluenesulfonate / tetrahydrofuran / 2.5 h / 20 °C
3.1: potassium carbonate / water; 1,2-dimethoxyethane / 9 h / 80 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / Cooling with ice; Inert atmosphere
4.2: 0.17 h
5.1: trifluoroacetic acid / chloroform / 1 h / 20 °C / Cooling with ice
With
thionyl chloride; pyridinium p-toluenesulfonate; sodium hydride; potassium carbonate; N,N-dimethyl-formamide; trifluoroacetic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; chloroform; water; N,N-dimethyl-formamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: pyridinium p-toluenesulfonate / tetrahydrofuran / 2.5 h / 20 °C
2.1: potassium carbonate / water; 1,2-dimethoxyethane / 9 h / 80 °C / Inert atmosphere
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / Cooling with ice; Inert atmosphere
3.2: 0.17 h
4.1: trifluoroacetic acid / chloroform / 1 h / 20 °C / Cooling with ice
With
pyridinium p-toluenesulfonate; sodium hydride; potassium carbonate; trifluoroacetic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; chloroform; water; N,N-dimethyl-formamide; mineral oil;
