(3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite

Base Information

• Chemical Name: (3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite
• CAS No.: 866550-21-2
• Molecular Formula: C₁₈H₁₉N₂OP
• Molecular Weight: 310.335
• Mol file: 866550-21-2.mol

Synonyms:(3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite

Chemical Property of (3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite

Chemical Property:

Purity/Quality:

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Technology Process of (3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite

There total 1 articles about (3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(Hydroxymethyl)-3,5-dimethylpyrazole (85264-33-1) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → (3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite (866550-21-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1016/j.jorganchem.2005.05.047

Reference yield: 85.0%

(3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite (866550-21-2) + [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) → [RuCl2(η6-p-cymene)((3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite)] (866550-13-2)

Guidance literature:

In dichloromethane; using vac. line and Schlenk techniques; ligand dissolved in CH2Cl2 addedto soln. of Ru complex in CH2Cl2; soln. stirred at room temp. for 16 h; soln. concd.; pptd. (cold Et2O); filtered off; elem. anal.;

DOI:10.1016/j.jorganchem.2005.05.047

upstream raw materials:

1-(Hydroxymethyl)-3,5-dimethylpyrazole

chloro-diphenylphosphine

Downstream raw materials:

[RuCl2(η6-p-cymene)((3,5-dimethyl-1H-pyrazol-1-yl)methyl diphenylphosphinite)]