FLUOREN-2-YLMETHYLAMINE

Base Information

• Chemical Name: FLUOREN-2-YLMETHYLAMINE
• CAS No.: 34577-93-0
• Molecular Formula: C14H13 N
• Molecular Weight: 195.264
• Hs Code.: 2921499090
• Mol file: 34577-93-0.mol

Synonyms:2-Fluorenemethylamine(2CI)

Chemical Property of FLUOREN-2-YLMETHYLAMINE

Chemical Property:

• Melting Point: 113 °C
• Boiling Point: 215 °C(Press: 10 Torr)
• PKA: 9.46±0.29(Predicted)
• PSA: 26.02000
• Density: 1.160±0.06 g/cm3(Predicted)
• LogP: 3.41680

Purity/Quality:

Fluoren-2-ylmethylamine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of FLUOREN-2-YLMETHYLAMINE

There total 7 articles about FLUOREN-2-YLMETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

fluorene-2-carboxaldehyde oxime → (9H-fluoren-2-yl)methanamine (34577-93-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; for 2h;

DOI:10.1021/jm701207m

Reference yield: 39.0%

2-cyanofluorene (2523-48-0) → (9H-fluoren-2-yl)methanamine (34577-93-0)

Guidance literature:

With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2016.09.041

Reference yield:

2-(bromomethyl)-9H-fluorene (78115-69-2) → (9H-fluoren-2-yl)methanamine (34577-93-0)

Guidance literature:

With ammonia; In ethanol; water; at 20 ℃; for 4h;

DOI:10.1021/ol403365

upstream raw materials:

2-cyanofluorene

decalin

9H-fluorene-2-carbaldehyde

(9H-Fluoren-2-yl)-methanol

Downstream raw materials:

N-((9H-fluoren-2-yl)methyl)-4-methylbenzenesulfonamide

N-((9H-fluoren-2-yl)methyl)-N-(1H-indol-2-yl)-4-methylbenzenesulfonamide

2-Chloromethyl-9H-fluorene

Refernces

• 1、 Kiruthika, Selvarangam E.,Perumal, Paramasivan Thirumalai. "CuI-catalyzed coupling of gem-dibromovinylanilides and sulfonamides: An efficient method for the synthesis of 2-amidoindoles and indolo[1,2-a] quinazolines". . p. 484 - 487. Retrieved 2014/04/03.