Technology Process of dibenzhydryl 2'-deoxygriseolate
There total 7 articles about dibenzhydryl 2'-deoxygriseolate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
azobisisobutyronitrile; tri-n-butyl-tin hydride;
In
benzene;
for 0.75h;
Heating;
DOI:10.1248/cpb.35.4442
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 87.6 percent / p-toluenesulfonic acid / dioxane / 2.5 h / Ambient temperature
2: 1.) 1 N aqueous sodium hydroxide; 2.) 3 N hydrochloric acid / 1) pH=7, r.t., 20 h; 2.) acetone, water, pH from 1.5 to 3,darkness
3: 70.6 percent / 4-(dimethylamino)pyridine / CH2Cl2 / Ambient temperature
4: lithium iodide / hexamethylphosphoric acid triamide / Ambient temperature
5: pyridine p-toluenesulfonate / CH2Cl2; ethanol / 8 h / 60 °C
6: 96.3 percent / α,α'-azobisisobutyronitrile, tributyltin hydride / benzene / 0.75 h / Heating
With
hydrogenchloride; dmap; sodium hydroxide; azobisisobutyronitrile; tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; toluene-4-sulfonic acid; lithium iodide;
In
1,4-dioxane; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; benzene;
DOI:10.1248/cpb.35.4442
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) 1 N aqueous sodium hydroxide; 2.) 3 N hydrochloric acid / 1) pH=7, r.t., 20 h; 2.) acetone, water, pH from 1.5 to 3,darkness
2: 70.6 percent / 4-(dimethylamino)pyridine / CH2Cl2 / Ambient temperature
3: lithium iodide / hexamethylphosphoric acid triamide / Ambient temperature
4: pyridine p-toluenesulfonate / CH2Cl2; ethanol / 8 h / 60 °C
5: 96.3 percent / α,α'-azobisisobutyronitrile, tributyltin hydride / benzene / 0.75 h / Heating
With
hydrogenchloride; dmap; sodium hydroxide; azobisisobutyronitrile; tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; lithium iodide;
In
N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; benzene;
DOI:10.1248/cpb.35.4442
