bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate

Base Information

• Chemical Name: bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate
• CAS No.: 156464-91-4
• Molecular Formula: C₁₆H₂₈NO₃P
• Molecular Weight: 313.377
• Mol file: 156464-91-4.mol

Synonyms:bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate

Chemical Property of bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate

There total 2 articles about bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

bis(1-methylethyl) (3-iodopropyl)phosphonate (156464-90-3) + N-methylaniline (100-61-8) → bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate (156464-91-4)

Guidance literature:

With sodium hydrogencarbonate; Heating;

DOI:10.1021/ja00094a019

Reference yield:

triisopropyl phosphite (116-17-6) → bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate (156464-91-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 2 h / Heating

2: 90 percent / aq. NaHCO₃ / Heating

With sodium hydrogencarbonate;

DOI:10.1021/ja00094a019

Reference yield:

bis(1-methylethyl) (3-(N-methyl-N-phenylamino)propyl)phosphonate (156464-91-4) → 3-(N-methyl-((4-((4-formylphenyl)azo)phenyl)amino)propyl)phosphonic acid

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) aq. HCl, NaNO₂, 2.) NaOAc / 1.) 5 deg C, 15 min, 2.) 5 deg C, 6 h

2: Me₃SiBr / CH₂Cl₂ / 16 h

With hydrogenchloride; trimethylsilyl bromide; sodium acetate; sodium nitrite; In dichloromethane;

DOI:10.1021/ja00094a019

upstream raw materials:

bis(1-methylethyl) (3-iodopropyl)phosphonate

N-methylaniline

triisopropyl phosphite