{2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone

Base Information

• Chemical Name: {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone
• CAS No.: 1416452-86-2
• Molecular Formula: C₂₉H₂₉BrO₃
• Molecular Weight: 505.451
• Mol file: 1416452-86-2.mol

Synonyms:{2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone

Chemical Property of {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone

There total 3 articles about {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

2-[4-(7-bromoheptyloxy)phenyl]benzofuran (1025740-45-7) + 4-methyl-benzoyl chloride (874-60-2) → {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone (1416452-86-2)

Guidance literature:

With tin(IV) chloride; In dichloromethane; at 20 ℃;

DOI:10.1016/j.ejmech.2012.10.045

Reference yield:

1,7-dibromoheptane (4549-31-9) → {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone (1416452-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 24 h / Reflux

2: tin(IV) chloride / dichloromethane / 20 °C

With tin(IV) chloride; potassium carbonate; In dichloromethane; acetone;

DOI:10.1016/j.ejmech.2012.10.045

Reference yield:

2-(4-hydroxyphenyl)benzo[b]furan (26870-36-0) → {2-[4-(7-bromoheptyloxy)phenyl]benzofuran-3-yl}-p-tolylmethanone (1416452-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 24 h / Reflux

2: tin(IV) chloride / dichloromethane / 20 °C

With tin(IV) chloride; potassium carbonate; In dichloromethane; acetone;

DOI:10.1016/j.ejmech.2012.10.045

upstream raw materials:

2-[4-(7-bromoheptyloxy)phenyl]benzofuran

4-methyl-benzoyl chloride

1,7-dibromoheptane

2-(4-hydroxyphenyl)benzo[b]furan

Downstream raw materials:

[2-(4-{7-[(3-hydroxybenzyl)-N-methylamino]heptyloxy}phenyl)benzofuran-3-yl]-p-tolylmethanone

C₃₉H₄₂N₂O₅