Sodium 1,1-difluoroethylsulfinate

Base Information

Chemical Name:Sodium 1,1-difluoroethylsulfinate
CAS No.:1422738-67-7
Molecular Formula:C₂H₃F₂O₂S*Na
Molecular Weight:152.097
Hs Code.:
Mol file:1422738-67-7.mol

Synonyms:sodium 1,1-difluoroethane-1-sulfinate

Suppliers and Price of Sodium 1,1-difluoroethylsulfinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Sodium 1,1-difluoroethanesulfinate
10g
$ 2670.00

Sigma-Aldrich
Sodium 1,1-difluoroethanesulfinate
1g
$ 314.00

Total 5 raw suppliers

Chemical Property of Sodium 1,1-difluoroethylsulfinate

Chemical Property:

Melting Point:>300°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Sodium 1,1-difluoroethanesulfinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:

Useful:

Uses DFES-Na provides a direct approach to fluorinated heteroarylether bioisosteres by appending a 1,1-difluoroethyl group operationally simple and robust protocol. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles. Learn More at the Professor and Product Portal of Professor Phil S. Baran. Baran Diversinates(TM) Lead Diversification and Metabolism Prediction Flyer

Technology Process of Sodium 1,1-difluoroethylsulfinate

There total 1 articles about Sodium 1,1-difluoroethylsulfinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 2-[(1,1-difluoroethyl)sulfonyl]pyridine

: 1422738-67-7
sodium 1,1-difluoroethane-1-sulfinate

Guidance literature:: With sodium hydride; ethanethiol; In tetrahydrofuran; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/anie.201300763

Reference yield: 88.0%

: 621-23-8
1,2,3-trimethoxybenzene

: 1422738-67-7
sodium 1,1-difluoroethane-1-sulfinate

: 1365122-33-3
1,3,5-trimethoxy-2-(trifluoromethyl)benzene

: 1,3,5-trimethoxy-2,4-bis(trifluoromethyl)benzene

Guidance literature:: With C₃₅H₃₇N₃O₂; In acetone; for 24h; Reagent/catalyst; Sealed tube; Inert atmosphere; Irradiation;
DOI:10.1039/c7cc05977a

Reference yield: 79.0%

: 1422738-67-7
sodium 1,1-difluoroethane-1-sulfinate

: 1-(4-bromophenyl)-3-(1-(3,4-dichlorophenyl)vinyl)-1,3-dimethylurea

: 1-(1-(4-bromophenyl)-1-(3,4-dichlorophenyl)-3,3-difluorobutyl)-1,3-dimethylurea

Guidance literature:: With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; caesium carbonate; In acetone; at 30 ℃; for 17h; Irradiation; Inert atmosphere;
DOI:10.1002/anie.202003632