4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Base Information

Chemical Name:4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate
CAS No.:143159-84-6
Molecular Formula:C₂₉H₂₂N₄O₇S₃
Molecular Weight:634.714
Hs Code.:

Synonyms:4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Suppliers and Price of 4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

There total 6 articles about 4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 143159-83-5
(E)-2-[(2R,3R)-2-(Benzothiazol-2-yldisulfanyl)-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-trifluoromethanesulfonyloxy-but-2-enoic acid 4-nitro-benzyl ester

: 143159-84-6
4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Guidance literature:: With triethylamine; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1016/S0040-4039(00)92502-4

Reference yield: 59.0%

: 4-nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-3-trifluoromethanesulfonyloxy-2-butenoate

: 143159-84-6
4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Guidance literature:: With triethylamine; In acetonitrile;

Reference yield:

: 41625-65-4
4-nitrobenzyl(2S,4S,5R,6R)-3,3-dimethyl-7-oxo-6-phenoxyacetamido-1-aza-4-thiabicyclo<3.2.0>heptane-2-carboxylate 4-oxide

: 143159-84-6
4-Nitrobenzyl 2-[(3R,4R)-4-[(benzothiazol-2-yl)dithio]-3-phenoxyacetamido-2-oxo-azetidin-1-yl]-2,3-butadienoate

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / toluene / Heating

2: 1.) O₃, 2.) Me₂S / 1.) MeOAc, -78 deg C

3: 87 percent / iPr₂NEt / CH₂Cl₂ / -78 °C

4: 100 percent / Et₃N / tetrahydrofuran / 1 h / Ambient temperature

With dimethylsulfide; ozone; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1016/S0040-4039(00)92502-4