(1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid

Base Information

Chemical Name:(1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid
CAS No.:244233-42-9
Molecular Formula:C₁₁H₁₄N₂O₂
Molecular Weight:206.244
Hs Code.:
DSSTox Substance ID:DTXSID70440732
Nikkaji Number:J1.160.940F
Wikidata:Q82257118
Mol file:244233-42-9.mol

Synonyms:244233-42-9;(1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid;DTXSID70440732;Cyclopropanecarboxylic acid, 1-amino-2-[(phenylamino)methyl]-, (1R,2S)- (9CI);(1R,2S)-1-Amino-2-(phenylaminomethyl)cyclopropanecarboxylic acid;Cyclopropanecarboxylic acid,1-amino-2-[(phenylamino)methyl]-,(1R,2S)-(9ci)

Suppliers and Price of (1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid

Chemical Property:

PSA：75.35000
LogP:1.67380
XLogP3:-1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:206.105527694
Heavy Atom Count:15
Complexity:251

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C1(C(=O)O)N)CNC2=CC=CC=C2
Isomeric SMILES:C1[C@H]([C@]1(C(=O)O)N)CNC2=CC=CC=C2

Technology Process of (1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid

There total 16 articles about (1R,2S)-1-Amino-2-(anilinomethyl)cyclopropane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 565237-68-5
(1R,3R,6S)-6-tert-butyl-5-methoxy-6-methyl-1-phenylaminomethyl-7-oxa-4-azaspiro[2.5]oct-4-en-8-one

: 244233-42-9,244233-43-0,565237-95-8
(1R,2S)-1-amino-2-(phenylaminomethyl)cyclopropanecarboxylic acid

Guidance literature:: (1R,3R,6S)-6-tert-butyl-5-methoxy-6-methyl-1-phenylaminomethyl-7-oxa-4-azaspiro[2.5]oct-4-en-8-one; With trifluoroacetic acid; In water; acetonitrile; at 60 ℃; for 20h;

With sodium hydroxide; In 1,2-dimethoxyethane; water; at 90 ℃; for 120h;
DOI:10.1002/ejoc.200390179

Reference yield: 50.0%

: 565237-70-9
(1S,3S,6S)-6-tert-butyl-5-methoxy-6-methyl-1-phenylaminomethyl-7-oxa-4-azaspiro[2.5]oct-4-en-8-one

: 244233-42-9,244233-43-0,565237-95-8
(1S,2S)-1-amino-2-(phenylaminomethyl)cyclopropanecarboxylic acid

Guidance literature:: (1S,3S,6S)-6-tert-butyl-5-methoxy-6-methyl-1-phenylaminomethyl-7-oxa-4-azaspiro[2.5]oct-4-en-8-one; With trifluoroacetic acid; In water; acetonitrile; at 60 ℃; for 20h;

With sodium hydroxide; In 2-ethoxy-ethanol; water; at 90 ℃; for 120h;
DOI:10.1002/ejoc.200390179