(2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester

Base Information

• Chemical Name: (2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester
• CAS No.: 1193376-30-5
• Molecular Formula: C₁₇H₂₀F₃NO₂
• Molecular Weight: 327.347
• Mol file: 1193376-30-5.mol

Synonyms:(2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester

Chemical Property of (2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester

There total 1 articles about (2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E,E)-octa-2,4-dien-1-ol (56904-85-9,69668-94-6,119518-99-9,119519-00-5,18409-20-6) + N-(4-methoxyphenyl)trifluoroacetimidoyl chloride (75999-66-5) → (2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester (1193376-30-5)

Guidance literature:

(E,E)-octa-2,4-dien-1-ol; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.0833333h; Inert atmosphere;

N-(4-methoxyphenyl)trifluoroacetimidoyl chloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1002/chem.200900712

Reference yield:

(2E,4E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid-octa-2,4-dienyl ester (1193376-30-5) → (S)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-pent-1-enylallyl)acetamide + (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-pent-1-enylallyl)acetamide (1193376-43-0)

Guidance literature:

With di-μ-chlorobis[η⁵-(S)-(S_p)-2-(2'-(4'-methylethyl)oxazolinyl)cyclopentadienyl, (1-C,3'-N)(η⁵-pentaphenylcyclopentadiene)ferrocene]dipalladium; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; silver nitrate; In dichloromethane; at 20 ℃; for 72h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1002/chem.200900712

upstream raw materials:

(E,E)-octa-2,4-dien-1-ol

N-(4-methoxyphenyl)trifluoroacetimidoyl chloride

Downstream raw materials:

(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-pent-1-enylallyl)acetamide