(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

Base Information

Chemical Name:(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester
CAS No.:104430-21-9
Molecular Formula:C₂₂H₃₁N₃O₈S
Molecular Weight:497.569
Hs Code.:

(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

Synonyms:(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

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Chemical Property of (2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

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Technology Process of (2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

There total 3 articles about (2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 54149-01-8
(pivaloyloxy)methyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

: 104430-21-9
(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride; In methanol; 1.) -30 deg C to 20 deg C for 1h, 2.) room temperature, 1h;
DOI:10.1002/bscb.19850941123

Reference yield:

: 18997-19-8
Chloromethyl pivalate

: 104430-21-9
(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / dimethylformamide / 24 h / Ambient temperature

2: 100 percent / hydroxylaminehydrochloride, NaOH / methanol / 1.) -30 deg C to 20 deg C for 1h, 2.) room temperature, 1h

With sodium hydroxide; hydroxylamine hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/bscb.19850941123

Reference yield:

: 132-98-9
penicillin V potassium

: 104430-21-9
(2R,4S)-2-[(R)-Hydroxycarbamoyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / dimethylformamide / 24 h / Ambient temperature

2: 100 percent / hydroxylaminehydrochloride, NaOH / methanol / 1.) -30 deg C to 20 deg C for 1h, 2.) room temperature, 1h

With sodium hydroxide; hydroxylamine hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/bscb.19850941123