(2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid

Base Information

Chemical Name:(2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid
CAS No.:244104-71-0
Molecular Formula:C₇H₁₁NO₃
Molecular Weight:157.169
Hs Code.:
DSSTox Substance ID:DTXSID00471599
Nikkaji Number:J1.148.609F
Wikidata:Q82300170
Mol file:244104-71-0.mol

Synonyms:244104-71-0;(2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid;DTXSID00471599;EN300-225859;(2S,4S)-4-methyl-6-oxopiperidine-2-carboxylicacid

Suppliers and Price of (2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid

Chemical Property:

PSA：69.89000
LogP:0.26160
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.07389321
Heavy Atom Count:11
Complexity:190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(NC(=O)C1)C(=O)O
Isomeric SMILES:C[C@H]1C[C@H](NC(=O)C1)C(=O)O

Technology Process of (2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid

There total 3 articles about (2S,4S)-4-methyl-6-oxopiperidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 678148-65-7
(-)-(4S,6S)-6-hydroxymethyl-4-methylpiperidin-2-one

: 244104-71-0
(-)-(2S,4S)-4-methyl-6-oxopipecolic acid

Guidance literature:: With dipyridinium dichromate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/S0040-4039(99)01047-3

Reference yield:

: 244104-69-6
(-)-(Ss,7'R)-7'-methyl-8'-[(4-methylphenyl)sulfinyl]-6',7'-dihydrospiro[cyclohexane-1,3'-[1,3]oxazolo[3,4-a]pyridin]-5'(1'H)-one

: 244104-71-0
(-)-(2S,4S)-4-methyl-6-oxopipecolic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / Raney nickel / ethanol / 1.5 h / Heating

2: 98 percent / AcOH / H₂O / 12 h / Heating

3: Jones reagent / acetone / 6 h / 0 - 25 °C

With jones reagent; acetic acid; nickel; In ethanol; water; acetone;
DOI:10.1016/S0957-4166(01)00553-5

Reference yield:

: 244104-70-9
(7'S,8a'S)-7'-methyltetrahydrospiro[cyclohexane-1,3'-[1,3]oxazolo[3,4-a]pyridin]-5'(1'H)-one

: 244104-71-0
(-)-(2S,4S)-4-methyl-6-oxopipecolic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / AcOH / H₂O / 12 h / Heating

2: Jones reagent / acetone / 6 h / 0 - 25 °C

With jones reagent; acetic acid; In water; acetone;
DOI:10.1016/S0957-4166(01)00553-5