5-Cyclopropyl-1-(quinolin-5-YL)-1H-pyrazole-4-carboxylic acid

Base Information

Chemical Name:5-Cyclopropyl-1-(quinolin-5-YL)-1H-pyrazole-4-carboxylic acid
CAS No.:241798-75-4
Molecular Formula:C₁₆H₁₃N₃O₂
Molecular Weight:279.298
Hs Code.:
UNII:89MF8FY9U6
ChEMBL ID:CHEMBL3526442
DSSTox Substance ID:DTXSID60461719
Nikkaji Number:J1.501.823B
Wikidata:Q82286112
Mol file:241798-75-4.mol

Synonyms:241798-75-4;5-CYCLOPROPYL-1-(QUINOLIN-5-YL)-1H-PYRAZOLE-4-CARBOXYLIC ACID;Zoniporide metabolite M3;5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid;5-cyclopropyl-1-quinolin-5-ylpyrazole-4-carboxylic acid;89MF8FY9U6;5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylic acid;1H-Pyrazole-4-carboxylicacid, 5-cyclopropyl-1-(5-quinolinyl)-;5-Cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxylic acid;1H-Pyrazole-4-carboxylic acid, 5-cyclopropyl-1-(5-quinolinyl)-;UNII-89MF8FY9U6;SCHEMBL6262880;CHEMBL3526442;DTXSID60461719;WSLKLYKPUZWAQW-UHFFFAOYSA-N;MFCD08704294;PS-19871;SY323810;F89858;5-cyclopropyl-1-quinolin-5-yl-1h-pyrazole4-carboxylic acid;5-cyclopropyl-1-(quinolin-5-yl)-1h-pyrazole-4-car-boxylic acid

Suppliers and Price of 5-Cyclopropyl-1-(quinolin-5-YL)-1H-pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-CYCLOPROPYL-1-QUINOLIN-5-YL-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00%
5MG
$ 501.85

Total 3 raw suppliers

Chemical Property of 5-Cyclopropyl-1-(quinolin-5-YL)-1H-pyrazole-4-carboxylic acid

Chemical Property:

Boiling Point:505.9±40.0 °C(Predicted)
PKA:3.45±0.36(Predicted)
PSA：68.01000
Density:1.46±0.1 g/cm3(Predicted)
LogP:2.99610
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:279.100776666
Heavy Atom Count:21
Complexity:412

Purity/Quality:

97% ^*data from raw suppliers

5-CYCLOPROPYL-1-QUINOLIN-5-YL-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1C2=C(C=NN2C3=CC=CC4=C3C=CC=N4)C(=O)O

Technology Process of 5-Cyclopropyl-1-(quinolin-5-YL)-1H-pyrazole-4-carboxylic acid

There total 5 articles about 5-Cyclopropyl-1-(quinolin-5-YL)-1H-pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 336881-24-4
5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid methyl ester

: 241798-75-4
5-cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: 5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid methyl ester; With sodium hydroxide; water; In methanol; at 65 ℃; for 1.5h; pH=1 - 2; Heating / reflux;

With hydrogenchloride; In water; at 20 ℃; for 0.5h; pH=1 - 2;