Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba

Base Information

• Chemical Name: Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba
• CAS No.: 1426656-22-5
• Molecular Formula: C₅₁H₉₀N₁₄O₈
• Molecular Weight: 1027.36
• Mol file: 1426656-22-5.mol

Synonyms:Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba

Chemical Property of Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba

There total 3 articles about Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C52H88N14O10 → Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba (1426656-22-5)

Guidance literature:

With palladium 10% on activated carbon; acetic acid; In methanol; at 20 ℃; for 1.5h; under 2844.39 Torr;

DOI:10.1021/acs.jmedchem.6b01499

Reference yield:

C69H114N14O13S → Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba (1426656-22-5)

Guidance literature:

With chlorotriisopropylsilane; water; trifluoroacetic acid; at 20 ℃; for 3h;

DOI:10.1002/cmdc.201500532

Reference yield:

C61H105N11O14S + 4-(aminomethyl)benzene-1-carboximidamide dihydrochloride (217313-79-6) → Ac-Leu-Leu-Leu-Leu-Arg-Val-Lys-4-Amba (1426656-22-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 6-chloro-1-hydroxybenzotriazole; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C

2: trifluoroacetic acid; chlorotriisopropylsilane; water / 3 h / 20 °C

With chlorotriisopropylsilane; water; N-ethyl-N,N-diisopropylamine; 6-chloro-1-hydroxybenzotriazole; trifluoroacetic acid; In N,N-dimethyl-formamide;

DOI:10.1002/cmdc.201500532

upstream raw materials:

4-(aminomethyl)benzene-1-carboximidamide dihydrochloride