3-Phenylbicyclo[1.1.1]pentan-1-amine hydrochloride

Base Information

Chemical Name:3-Phenylbicyclo[1.1.1]pentan-1-amine hydrochloride
CAS No.:83249-11-0
Molecular Formula:C₁₁H₁₃N*ClH
Molecular Weight:195.692
Hs Code.:
European Community (EC) Number:846-103-1

Synonyms:3-phenylbicyclo[1.1.1]pentan-1-amine hydrochloride;83249-11-0;3-Phenylbicyclo[1.1.1]pentan-1-amine HCl;3-phenylbicyclo[1.1.1]pentan-1-amine;hydrochloride;SCHEMBL22362678;MFCD28012200;AKOS026745078;BS-46009;CS-0081006;EN300-171116;P19163;EN300-37374031;3-phenylbicyclo[1.1.1]pentan-1-aminehydrochloride;Z2417838028

Suppliers and Price of 3-Phenylbicyclo[1.1.1]pentan-1-amine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 3-Phenylbicyclo[1.1.1]pentan-1-amine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:195.0814771
Heavy Atom Count:13
Complexity:183

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2(CC1(C2)N)C3=CC=CC=C3.Cl

Technology Process of 3-Phenylbicyclo[1.1.1]pentan-1-amine hydrochloride

There total 4 articles about 3-Phenylbicyclo[1.1.1]pentan-1-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: (3-phenylbicyclo[1.1.1]pentan-1-yl)hydrazine hydrochloride

: 83249-11-0
1-phenylbicyclo<1.1.1>pent-3-ylamine hydrochloride

Guidance literature:: With platinum(IV) oxide; hydrogen; In methanol; at 20 ℃; for 12h; under 760.051 Torr;
DOI:10.1021/jacs.7b11865

Reference yield: 51.0%

: 83249-04-1
3-phenylbicyclo<1.1.1>pentane-1-carboxylic acid

: 83249-11-0
1-phenylbicyclo<1.1.1>pent-3-ylamine hydrochloride

Guidance literature:: With hydrogen azide; sulfuric acid; In chloroform; at 40 ℃; for 2h;
DOI:10.1021/jo00146a031

Reference yield:

: 65862-03-5
methyl 3-phenyl-2,2-dichlorobicyclo<1.1.1>pentanecarboxylate

: 83249-11-0
1-phenylbicyclo<1.1.1>pent-3-ylamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) tri-n-butyltin hydride, azobis(isobutyronitrile), 2.) NaOH / 1.) 130 deg C, 76 h, 2.) H₂O, heating, 2 h

2: 51 percent / concd H₂SO₄, hydrazoic acid / CHCl₃ / 2 h / 40 °C

With sodium hydroxide; hydrogen azide; 2,2'-azobis(isobutyronitrile); sulfuric acid; tri-n-butyl-tin hydride; In chloroform;
DOI:10.1021/jo00146a031