C₆₉H₇₂ClNO₂₀

Base Information

• Chemical Name: C₆₉H₇₂ClNO₂₀
• CAS No.: 152932-92-8
• Molecular Formula: C₆₉H₇₂ClNO₂₀
• Molecular Weight: 1270.78
• Mol file: 152932-92-8.mol

Synonyms:C₆₉H₇₂ClNO₂₀

Chemical Property of C₆₉H₇₂ClNO₂₀

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₆₉H₇₂ClNO₂₀

There total 7 articles about C₆₉H₇₂ClNO₂₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C62H65ClFNO19 (152932-87-1) + benzyl alcohol (100-51-6,185532-71-2) → C69H72ClNO20 (152932-92-8)

Guidance literature:

With bis(cyclopentadienyl)hafnium dichloride; 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; at 0 - 25 ℃; for 18h;

DOI:10.1021/ja00072a049

Reference yield:

2,3,4-tri-O-benzyl-L-fucopyranosyl fluoride (127061-08-9) → C69H72ClNO20 (152932-92-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / AgClO₄, SnCl₂, 4A-molecular sieves / diethyl ether; tetrahydrofuran / 1 h / -10 - 0 °C

2: 80 percent / DAST, NBS / CH₂Cl₂ / 2 h / -78 - -20 °C

3: 95 percent / Cp₂HfCl₂, AgOTf, 4A molecular sieves / CH₂Cl₂ / 18 h / 0 - 25 °C

With N-Bromosuccinimide; bis(cyclopentadienyl)hafnium dichloride; 4 A molecular sieve; silver trifluoromethanesulfonate; silver perchlorate; 4,4'-diaminostilbene-2,2'-disulfonic acid; tin(ll) chloride; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1021/ja00072a049

Reference yield:

Chloro-acetic acid (2R,3S,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-fluoro-tetrahydro-pyran-4-yl ester → C69H72ClNO20 (152932-92-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 63 percent / AgOTf, Cp₂HfCl₂, 2,6-di-tert-butyl-4-methylpyridine, 4A-molecular sieves / CH₂Cl₂ / 6 h / 0 - 25 °C

2: 76 percent / NaCNBH₃, HCl, 3A-molecular sieves / diethyl ether; tetrahydrofuran / 0.5 h / 0 °C

3: 95 percent / AgClO₄, SnCl₂, 4A-molecular sieves / diethyl ether; tetrahydrofuran / 1 h / -10 - 0 °C

4: 80 percent / DAST, NBS / CH₂Cl₂ / 2 h / -78 - -20 °C

5: 95 percent / Cp₂HfCl₂, AgOTf, 4A molecular sieves / CH₂Cl₂ / 18 h / 0 - 25 °C

With hydrogenchloride; N-Bromosuccinimide; 2,6-di-tert-butyl-4-methylpyridine; bis(cyclopentadienyl)hafnium dichloride; 3 A molecular sieve; 4 A molecular sieve; silver trifluoromethanesulfonate; silver perchlorate; sodium cyanoborohydride; 4,4'-diaminostilbene-2,2'-disulfonic acid; tin(ll) chloride; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1021/ja00072a049

upstream raw materials:

C₆₂H₆₅ClFNO₁₉

benzyl alcohol

2,3,4-tri-O-benzyl-L-fucopyranosyl fluoride

phenyl 4,6-di-O-benzylidene-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Downstream raw materials:

C₅₅H₆₅NO₁₈S

C₆₇H₇₁NO₂₂S