8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid

Base Information

• Chemical Name: 8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid
• CAS No.: 109898-75-1
• Molecular Formula: C₂₅H₃₇N₃O₇
• Molecular Weight: 491.585
• Mol file: 109898-75-1.mol

Synonyms:8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid

Chemical Property of 8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid

There total 1 articles about 8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 9-hydroxynonanoate (34957-73-8) + Acetic acid (2R,3S,4S,5R,6R)-3-azido-5-benzyloxy-6-bromo-2-methyl-tetrahydro-pyran-4-yl ester → 8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid (109898-75-1)

Guidance literature:

With 4 A molecular sieve; N,N-dimethyl-formamide; tetraethylammonium bromide; Yield given. Multistep reaction; 1.) dichloromethane, 4 d, r.t., 2.) dichloromethane, r.t., 8 d;

DOI:10.1016/0008-6215(86)80006-4

Reference yield: 99.0%

8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid (109898-75-1) → 8-methoxycarbonyloctyl 4-azido-2-O-benzyl-4,6-dideoxy-α-D-galactopyranoside (97783-80-7)

Guidance literature:

With sodium methylate; In methanol; for 5.5h; Ambient temperature;

DOI:10.1016/0008-6215(86)80006-4

Reference yield:

8-Methoxycarbonyloctyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid (109898-75-1) → 8-methoxycarbonyloctyl O--(1->4)-O-(6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-(1->3)-4-azido-2-O-benzyl-4,6-dideoxy-α-D-galactopyranoside

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / natriummethoxyde 1percent in MeOH / methanol / 5.5 h / Ambient temperature

2: 1.) Ag₂CO₃, molecular sieves 4 Angstroem, 2.) AgClO₄ / 1.) dichloromethane, r.t., 2 h, 2.) dichloromethane, r.t.,

With 4 A molecular sieve; sodium methylate; silver perchlorate; silver carbonate; In methanol;

DOI:10.1016/0008-6215(86)80006-4

upstream raw materials:

methyl 9-hydroxynonanoate

Downstream raw materials:

8-methoxycarbonyloctyl 4-azido-2-O-benzyl-4,6-dideoxy-α-D-galactopyranoside

8-Methoxycarbonyloctyl-O--(1->4)-O-(2-acetamido-6-O-acetyl-3-O-benzyl-2-desoxy-α-D-glucopyranosyl)-(1->3)4-acetamido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid