2-[3-(Carboxymethoxy)-6-oxoxanthen-9-YL]benzoic acid

Base Information

Chemical Name:2-[3-(Carboxymethoxy)-6-oxoxanthen-9-YL]benzoic acid
CAS No.:233759-98-3
Molecular Formula:C₂₂H₁₄O₇
Molecular Weight:390.349
Hs Code.:2932999099
European Community (EC) Number:634-992-7
DSSTox Substance ID:DTXSID00585004
Nikkaji Number:J2.132.969J
Wikidata:Q82476780
Mol file:233759-98-3.mol

Synonyms:FOAA;233759-98-3;Fluorescein-O'-acetic acid;FLUORESCEIN-O'-ACETIC ACID*;2-[3-(CARBOXYMETHOXY)-6-OXOXANTHEN-9-YL]BENZOIC ACID;2-(6-(Carboxymethoxy)-3-oxo-3H-xanthen-9-yl)benzoic acid;2-[6-(CARBOXYMETHOXY)-3-OXO-3H-XANTHEN-9-YL]BENZOIC ACID;SCHEMBL10268461;DTXSID00585004;MFCD05865263;J-100158;Fluorescein-O'-acetic acid, suitable for fluorescence, BioReagent, >=90% (HPCE);892155-59-8

Suppliers and Price of 2-[3-(Carboxymethoxy)-6-oxoxanthen-9-YL]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Fluorescein-O′-acetic acid
5mg
$ 70.00

Sigma-Aldrich
Fluorescein-O′-acetic acid BioReagent, suitable for fluorescence, ≥90% (HPCE)
25mg-f
$ 390.00

Sigma-Aldrich
Fluorescein-O′-acetic acid BioReagent, suitable for fluorescence, ≥90% (HPCE)
5mg-f
$ 103.00

American Custom Chemicals Corporation
FLUORESCEIN-O-ACETATE 95.00%
5MG
$ 495.58

Adipogen Life Sciences
FOAA ≥90%(HPCE)
5 mg
$ 81.00

Total 3 raw suppliers

Chemical Property of 2-[3-(Carboxymethoxy)-6-oxoxanthen-9-YL]benzoic acid

Chemical Property:

Vapor Pressure:1.19E-21mmHg at 25°C
Refractive Index:1.721
Boiling Point:718.2°C at 760 mmHg
Flash Point:259.6°C
PSA：114.04000
Density:1.55g/cm³
LogP:3.72640
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:390.07395278
Heavy Atom Count:29
Complexity:806

Purity/Quality:

98%Min ^*data from raw suppliers

Fluorescein-O′-acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/38
Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=C3C=CC(=O)C=C3OC4=C2C=CC(=C4)OCC(=O)O)C(=O)O
Uses Fluorescent label which reacts with amines after activation to give isomerically homogeneous derivatives. Fluorescein-O''-acetic acid is a fluorescent label which reacts with amines after activation to give isomerically homogeneous derivatives. It is a fluorescent label.

Technology Process of 2-[3-(Carboxymethoxy)-6-oxoxanthen-9-YL]benzoic acid

There total 4 articles about 2-[3-(Carboxymethoxy)-6-oxoxanthen-9-YL]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 824424-13-7
tert-butyl 2-((3′-hydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthen]-6′-yl)oxy)acetate

: 233759-98-3
O-carboxymethyl fluorescein

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 1h;
DOI:10.1021/acs.bioconjchem.1c00205

Reference yield:

: 3-isocyanopropyl resorufin ether

: C₂₉H₂₄N₄O₇

: 635-78-9
resorufin

: 233759-98-3
O-carboxymethyl fluorescein

Guidance literature:: In dimethyl sulfoxide; at 37 ℃; for 8h; pH=7.4;
DOI:10.1039/c9sc04649f

Reference yield:

: 2321-07-5,126605-73-0
fluorescein

: 233759-98-3
O-carboxymethyl fluorescein

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide / water

2: trifluoroacetic acid / dichloromethane / 1 h

With trifluoroacetic acid; lithium hydroxide; In dichloromethane; water;
DOI:10.1021/acs.bioconjchem.1c00205