phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside

Base Information

• Chemical Name: phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside
• CAS No.: 179072-68-5
• Molecular Formula: C₂₇H₂₈O₆S
• Molecular Weight: 480.582

Synonyms:phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside

Chemical Property of phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside

There total 4 articles about phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.4%

benzaldehyde dimethyl acetal (1125-88-8) + phenyl 3-O-(4-methoxybenzyl)-1-thio-β-D-galactopyranoside (179072-63-0) → phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside (179072-68-5)

Guidance literature:

With camphor-10-sulfonic acid; In N,N-dimethyl-formamide; at 45 ℃; for 0.5h;

DOI:10.1016/0040-4039(96)00901-X

Reference yield: 87.0%

phenyl 4,6-di-O-benzylidene-1-thio-β-D-galactopyranoside (71676-30-7,87508-17-6,138922-03-9,87508-18-7) + p-methoxybenzyl chloride (824-94-2) → phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside (179072-68-5)

Guidance literature:

phenyl 4,6-di-O-benzylidene-1-thio-β-D-galactopyranoside; With di(n-butyl)tin oxide; In toluene; at 110 ℃; for 3h;

p-methoxybenzyl chloride; With tetra-(n-butyl)ammonium iodide; In toluene; at 25 - 110 ℃; for 2h;

DOI:10.1002/(SICI)1521-3773(19991115)38:22<3345::AID-ANIE3345>3.0.CO;2-9

Reference yield:

1-thiophenyl-β-D-galactopyranoside (16758-34-2) → phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside (179072-68-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Bu₂SnO; 2.) CsF / 1.) MeOH, reflux, 2 h; 2.) DMF, 50 deg C, 2 d

2: 92.4 percent / camphorsulfonic acid / dimethylformamide / 0.5 h / 45 °C

With camphor-10-sulfonic acid; di(n-butyl)tin oxide; cesium fluoride; In N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(96)00901-X

upstream raw materials:

benzaldehyde dimethyl acetal

phenyl 3-O-(4-methoxybenzyl)-1-thio-β-D-galactopyranoside

phenyl 4,6-di-O-benzylidene-1-thio-β-D-galactopyranoside

p-methoxybenzyl chloride

Downstream raw materials:

4-Oxo-pentanoic acid (2S,4aR,6S,7R,8S,8aS)-8-(4-methoxy-benzyloxy)-2-phenyl-6-phenylsulfanyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester

tert-Butyl-[(2S,4aR,6S,7R,8S,8aS)-8-(4-methoxy-benzyloxy)-2-phenyl-6-phenylsulfanyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy]-dimethyl-silane

S-phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-2-O-pivaloyl-1-thio-β-D-galactopyranoside

(2R,3S,4S,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-2-methyl-6-phenylsulfanyl-tetrahydro-pyran-3-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 179072-68-5 phenyl 4,6-O-benzylidene-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send