Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate

Base Information

Chemical Name:Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate
CAS No.:232597-44-3
Molecular Formula:C₁₃H₁₉NO₃
Molecular Weight:237.299
Hs Code.:2924299090
DSSTox Substance ID:DTXSID50378044
Nikkaji Number:J2.354.214E,J3.262.644K
Mol file:232597-44-3.mol

Synonyms:232597-44-3;Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate;1-(4-boc-amino-phenyl)-ethanol;tert-butyl 4-(1-hydroxyethyl)phenylcarbamate;tert-Butyl (4-(1-hydroxyethyl)phenyl)carbamate;DTXSID50378044;MFCD06245420;AKOS005257410;AB17369;1-(4-Aminophenyl)ethanol, N-BOC protected;tert-Butyl(4-(1-hydroxyethyl)phenyl)carbamate;EN300-233935;[4-(1-Hydroxyethyl)phenyl]carbamic acid tert-butyl ester;(?)-alpha-Methyl-4-(tert-butoxycarbonylamino)benzenemethanol;904814-06-8

Suppliers and Price of Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-(4-Aminophenyl)ethanol, N-Boc protected
50 mg
$ 154.00

American Custom Chemicals Corporation
1-(4-BOC-AMINO-PHENYL)-ETHANOL 95.00%
50MG
$ 717.21

Total 4 raw suppliers

Chemical Property of Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate

Chemical Property:

Vapor Pressure:0.000175mmHg at 25°C
Refractive Index:1.554
Boiling Point:316.3°Cat760mmHg
PKA:13.78±0.70(Predicted)
Flash Point:145.1°C
PSA：58.56000
Density:1.132g/cm³
LogP:3.15990
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:237.13649347
Heavy Atom Count:17
Complexity:252

Purity/Quality:

95% ^*data from raw suppliers

1-(4-Aminophenyl)ethanol, N-Boc protected ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)NC(=O)OC(C)(C)C)O

Technology Process of Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate

There total 2 articles about Tert-butyl N-[4-(1-hydroxyethyl)phenyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 57295-14-4
tert-butyl 4-vinylphenylcarbamate

: 232597-44-3,904814-06-8,934692-07-6
tert-butyl (4-[1-hydroxyethyl]phenyl)carbamate

: 232597-42-1
tert-butyl 4-acetylphenylcarbamate

Guidance literature:: With triethylsilane; (1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-Hexadecafluorophthalocyaninato)iron(II); oxygen; In ethanol; at 20 ℃; for 18h; under 760.051 Torr; chemoselective reaction; Sealed tube; Green chemistry;
DOI:10.1002/anie.201710370

Reference yield: 59.0%

: 232597-42-1
tert-butyl 4-acetylphenylcarbamate

: 232597-44-3,904814-06-8,934692-07-6
tert-butyl (4-[1-hydroxyethyl]phenyl)carbamate

Guidance literature:: With carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II); Butane-1,4-diol; In 1,2-dimethoxyethane; at 115 ℃; for 24h; Inert atmosphere;
DOI:10.1002/ejoc.201301020

Reference yield: 98.0%

: 108-22-5
Isopropenyl acetate

: 232597-44-3,904814-06-8,934692-07-6
tert-butyl (4-[1-hydroxyethyl]phenyl)carbamate

: 1286240-16-1
(R)-1-(N-Boc-4-aminophenyl)ethyl acetate

Guidance literature:: With dicarbonylchlorido(pentabenzylcyclopentadienyl)ruthenium; potassium tert-butylate; sodium carbonate; In tetrahydrofuran; toluene; at 23 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere; dynamic kinetic resolution; Enzymatic reaction;
DOI:10.1002/ejoc.201001703