1-hydroxy-1,1,2-ethanetricarboxylic acid

Base Information

• Chemical Name: 1-hydroxy-1,1,2-ethanetricarboxylic acid
• CAS No.: 110863-50-8
• Molecular Formula: C₅H₆O₇
• Molecular Weight: 178.098
• Mol file: 110863-50-8.mol

Synonyms:1-hydroxy-1,1,2-ethanetricarboxylic acid

Chemical Property of 1-hydroxy-1,1,2-ethanetricarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-hydroxy-1,1,2-ethanetricarboxylic acid

There total 2 articles about 1-hydroxy-1,1,2-ethanetricarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-3-deoxy-2-C-hydroxymethyl-tetrono-1,4-lactone (19444-86-1) → 1-hydroxy-1,1,2-ethanetricarboxylic acid (110863-50-8) + C17H40O6Si4 + C17H42O5Si4 (55521-19-2) + C11H22O5Si2 + C11H22O5Si2 + C15H36O6Si4 (42827-95-2)

Guidance literature:

With calcium hydroxide; trimethylsilylation agent; nitric acid; Product distribution; multistep reaction for structure determination of oxidation products;

DOI:10.1016/S0008-6215(00)90045-4

Reference yield:

C5H7NO6 → malic acid (617-48-1,78644-42-5) + 1-hydroxy-1,1,2-ethanetricarboxylic acid (110863-50-8)

Guidance literature:

With water; zinc(II) cation; at 50 ℃; pH=5 - 6;

DOI:10.1038/s41557-021-00878-w

Reference yield: 53.0%

4-hydroxy-N,N,1,2-tetramethyl-5-[3-(2-methylphenyl)-3-oxopropyl]-1H-benzimidazole-6-carboxamide (917957-35-8) + 1-hydroxy-1,1,2-ethanetricarboxylic acid (110863-50-8) → 4-hydroxy-N,N,1,2-tetramethyl-5-(3-(2-methylphenyl)-3-oxopropyl)-1H-benzimidazole-6-carboxamide citrate (1: 1.75)

Guidance literature:

In butan-1-ol; at 20 ℃; for 60h;

upstream raw materials:

DL-3-deoxy-2-C-hydroxymethyl-tetrono-1,4-lactone