(+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester

Base Information

• Chemical Name: (+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester
• CAS No.: 860791-93-1
• Molecular Formula: C₂₄H₂₁NO₂S
• Molecular Weight: 387.502
• Mol file: 860791-93-1.mol

Synonyms:(+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester

Chemical Property of (+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester

There total 1 articles about (+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-(2-mercaptophenyl)-pyrrole (43153-76-0) + ethyl 2-bromo-2-(naphth-1-yl)acetate (96155-82-7) → (+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester (860791-93-1)

Guidance literature:

1-(2-mercaptophenyl)-pyrrole; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h;

ethyl 2-bromo-2-(naphth-1-yl)acetate; In tetrahydrofuran; at 20 ℃; for 17h;

DOI:10.1021/jm049402y

Reference yield: 70.0%

(+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid ethyl ester (860791-93-1) → (+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid (860791-96-4)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

DOI:10.1021/jm049402y

upstream raw materials:

1-(2-mercaptophenyl)-pyrrole

ethyl 2-bromo-2-(naphth-1-yl)acetate

Downstream raw materials:

(+/-)-α-[[2-(1H-pyrrol-1-yl)phenyl]thio]naphth-1-ylacetic acid