Technology Process of (E)-3-methyl-6-(2,3,3-trimethyl-1-cyclopenten-1-yl)-4-hexen-1-ol tosylate
There total 6 articles about (E)-3-methyl-6-(2,3,3-trimethyl-1-cyclopenten-1-yl)-4-hexen-1-ol tosylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: conc. HCl / 24 h / Heating
2: 2.) Et3N / 1.) Et2O, 24 h, 2.) ethanol
3: 87 percent / diisobutyl aluminium hydride / hexane / 2 h / -70 °C
4: 88.4 percent / propionic acid / 1 h / 138 °C
5: 96 percent / LiAlH4 / diethyl ether; diethyl ether / 10 h
6: pyridine / 6 h
With
pyridine; hydrogenchloride; lithium aluminium tetrahydride; diisobutylaluminium hydride; propionic acid; triethylamine;
In
diethyl ether; hexane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2.) Et3N / 1.) Et2O, 24 h, 2.) ethanol
2: 87 percent / diisobutyl aluminium hydride / hexane / 2 h / -70 °C
3: 88.4 percent / propionic acid / 1 h / 138 °C
4: 96 percent / LiAlH4 / diethyl ether; diethyl ether / 10 h
5: pyridine / 6 h
With
pyridine; lithium aluminium tetrahydride; diisobutylaluminium hydride; propionic acid; triethylamine;
In
diethyl ether; hexane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87 percent / diisobutyl aluminium hydride / hexane / 2 h / -70 °C
2: 88.4 percent / propionic acid / 1 h / 138 °C
3: 96 percent / LiAlH4 / diethyl ether; diethyl ether / 10 h
4: pyridine / 6 h
With
pyridine; lithium aluminium tetrahydride; diisobutylaluminium hydride; propionic acid;
In
diethyl ether; hexane;
