4-((ethoxymethoxy)methyl)-2-methoxy phenol

Base Information

• Chemical Name: 4-((ethoxymethoxy)methyl)-2-methoxy phenol
• CAS No.: 1058649-10-7
• Molecular Formula: C₁₁H₁₆O₄
• Molecular Weight: 212.246
• Mol file: 1058649-10-7.mol

Synonyms:4-((ethoxymethoxy)methyl)-2-methoxy phenol

Chemical Property of 4-((ethoxymethoxy)methyl)-2-methoxy phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-((ethoxymethoxy)methyl)-2-methoxy phenol

There total 1 articles about 4-((ethoxymethoxy)methyl)-2-methoxy phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

formaldehyde diethyl acetal (462-95-3) + 4-hydroxymethyl-2-methoxyphenol (498-00-0) → 4-((ethoxymethoxy)methyl)-2-methoxy phenol (1058649-10-7)

Guidance literature:

phosphotungstic acid; at 20 ℃; for 3h;

DOI:10.1139/V08-068

Reference yield: 94.0%

4-((ethoxymethoxy)methyl)-2-methoxy phenol (1058649-10-7) + acetic anhydride (108-24-7) → 4-acetoxymethyl-2-methoxyphenol (57404-55-4)

Guidance literature:

With 1-methylimidazole hydrogen sulfate; at 120 ℃; for 0.0416667h; chemoselective reaction; Microwave irradiation;

DOI:10.1007/s00706-010-0373-6

Reference yield: 93.0%

4-((ethoxymethoxy)methyl)-2-methoxy phenol (1058649-10-7) → 4-hydroxymethyl-2-methoxyphenol (498-00-0)

Guidance literature:

With 1-methylimidazole hydrogen sulfate; at 120 ℃; for 0.0333333h; chemoselective reaction; Microwave irradiation;

DOI:10.1007/s00706-010-0373-6

upstream raw materials:

formaldehyde diethyl acetal

4-hydroxymethyl-2-methoxyphenol

Downstream raw materials:

4-hydroxymethyl-2-methoxyphenol

4-hydroxy-3-methoxyphenylacetonitrile

4-acetoxymethyl-2-methoxyphenyl acetate

(2-methoxy-4-((trimethylsilyloxy)methyl)phenoxy)trimethylsilane