tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate

Base Information

Chemical Name:tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate
CAS No.:478404-63-6
Molecular Formula:C₁₉H₂₉F₂NO₄
Molecular Weight:373.44
Hs Code.:

Synonyms:tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate

Chemical Property:

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Technology Process of tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate

There total 1 articles about tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 362480-02-2
(S)-[1-(3,5-difluorobenzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

: VCl₃(THF)3

: N-(tert-butoxycarbonyl)-3,5-difluoro-N-methoxy-N-methyl-L-phenylalaninamide

: 110-62-3
pentanal

: 478404-63-6
tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate

Guidance literature:: With potassium hydrogensulfate; LiAlH₄; zinc; In tetrahydrofuran; dichloromethane;

Reference yield: 1.0%

: 388071-09-8
3-bromo-5-(dipropylcarbamoyl)benzoic acid

: 478404-63-6
tert-butyl (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylcarbamate

: 478404-62-5
5-Bromo-N-[(1S,2R,3R)-1-(3,5-difluoro-benzyl)-2,3-dihydroxy-heptyl]-N',N'-dipropyl-isophthalamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;