2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile

Base Information

• Chemical Name: 2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile
• CAS No.: 1558009-73-6
• Molecular Formula: C₁₈H₁₀N₆O₂S
• Molecular Weight: 374.382
• Mol file: 1558009-73-6.mol

Synonyms:2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile

Chemical Property of 2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile

There total 2 articles about 2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-Sulfanylpyridine (2637-34-5,73018-10-7) + 4-nitrobenzaldehdye (555-16-8) + malononitrile (109-77-3) → 4-nitrobenzylmalononitrile (6731-53-9) + 2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile (1558009-73-6)

Guidance literature:

With potassium carbonate; In neat (no solvent); at 20 ℃; for 0.583333h; Green chemistry;

DOI:10.1248/cpb.c13-00412

Reference yield:

2-Sulfanylpyridine (2637-34-5,73018-10-7) + 4-nitrobenzaldehdye (555-16-8) + malononitrile (109-77-3) → 2-amino-4-(4-nitrophenyl)-6-(pyridine-2-ylthio)pyridine-3,5-dicarbonitrile (1558009-73-6)

Guidance literature:

With natural dolomitic limestone; In ethanol; water; at 45 - 50 ℃; for 0.533333h; Sonication; Green chemistry;

DOI:10.3762/BJOC.16.156

upstream raw materials:

2-Sulfanylpyridine

4-nitrobenzaldehdye

malononitrile