C₅₀H₅₃N₃O₈

Base Information

• Chemical Name: C₅₀H₅₃N₃O₈
• CAS No.: 947747-45-7
• Molecular Formula: C₅₀H₅₃N₃O₈
• Molecular Weight: 823.986
• Mol file: 947747-45-7.mol

Synonyms:C₅₀H₅₃N₃O₈

Chemical Property of C₅₀H₅₃N₃O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₀H₅₃N₃O₈

There total 14 articles about C₅₀H₅₃N₃O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C47H52N4O9 (947747-23-1) + 1-Pentyne (627-19-0) → C50H53N3O8 (947747-45-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2007.05.161

Reference yield:

C43H42O7S (947747-35-5) → C50H53N3O8 (947747-45-7)

Guidance literature:

Multi-step reaction with 8 steps

1: 94 percent / NaN₃ / dimethylformamide

2: 86 percent / PPTs / methanol

3: 64 percent / MeOTf / CH₂Cl₂

4: 81 percent / DDQ / CH₂Cl₂; methanol

5: 91 percent / TPAP; NMO; MS₄A / acetonitrile

6: 85 percent / NaClO₂; NaH₂PO₄; 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O

7: 90 percent / EDC*HCl / CH₂Cl₂

8: 80 percent / BuLi / tetrahydrofuran

With sodium chlorite; sodium dihydrogenphosphate; n-butyllithium; sodium azide; N-methyl-2-indolinone; tetrapropylammonium perruthennate; 2-methyl-but-2-ene; pyridinium p-toluenesulfonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; methyl trifluoromethanesulfonate; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.tetlet.2007.05.161

Reference yield:

C42H40O5 (947747-20-8) → C50H53N3O8 (947747-45-7)

Guidance literature:

Multi-step reaction with 9 steps

1: 88 percent / pyridine

2: 94 percent / NaN₃ / dimethylformamide

3: 86 percent / PPTs / methanol

4: 64 percent / MeOTf / CH₂Cl₂

5: 81 percent / DDQ / CH₂Cl₂; methanol

6: 91 percent / TPAP; NMO; MS₄A / acetonitrile

7: 85 percent / NaClO₂; NaH₂PO₄; 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O

8: 90 percent / EDC*HCl / CH₂Cl₂

9: 80 percent / BuLi / tetrahydrofuran

With sodium chlorite; sodium dihydrogenphosphate; n-butyllithium; sodium azide; N-methyl-2-indolinone; tetrapropylammonium perruthennate; 2-methyl-but-2-ene; pyridinium p-toluenesulfonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; methyl trifluoromethanesulfonate; In tetrahydrofuran; pyridine; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.tetlet.2007.05.161

upstream raw materials:

C₄₇H₅₂N₄O₉

1-Pentyne

C₄₂H₄₀O₅

C₄₃H₄₂O₇S

Downstream raw materials:

C₅₀H₅₅N₃O₈

C₅₇H₆₁N₃O₈

C₈₁H₁₀₉NO₉

OCH