L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate)

Base Information

Chemical Name:L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate)
CAS No.:228115-91-1
Molecular Formula:C₃₅H₃₈O₈S
Molecular Weight:618.748
Hs Code.:

Synonyms:L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate)

Suppliers and Price of L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate)

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate)

There total 16 articles about L-glycero-L-galacto-Heptitol, 2,6-anhydro-3,4,5-tris-O-(phenylmethyl)-, 1-(4-methylbenzenesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 98-59-9
p-toluenesulfonyl chloride

: 228115-90-0
2,6-anhydro-3,4,5-tri-O-benzyl-L-glycero-L-galacto-heptitol

: 228115-91-1
Toluene-4-sulfonic acid (2R,3S,4R,5S,6S)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl ester

: 228115-91-1
Toluene-4-sulfonic acid (2S,3S,4S,5S,6R)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl ester

: 228115-93-3
C₄₂H₄₄O₁₀S₂

Guidance literature:: With pyridine; In dichloromethane; for 96h;
DOI:10.1016/S0040-4020(99)00327-0

Reference yield: 29.0%

: 98-59-9
p-toluenesulfonyl chloride

: 228115-90-0
2,6-anhydro-3,4,5-tri-O-benzyl-L-glycero-L-galacto-heptitol

: 228115-91-1
Toluene-4-sulfonic acid (2R,3S,4R,5S,6S)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl ester

: 228115-91-1
Toluene-4-sulfonic acid (2S,3S,4S,5S,6R)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl ester

: 228115-93-3
C₄₂H₄₄O₁₀S₂

Guidance literature:: With pyridine; In dichloromethane; for 96h;
DOI:10.1016/S0040-4020(99)00327-0

Reference yield:

: 52443-07-9
3,4,5,7-tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptonitrile

: 228115-91-1
Toluene-4-sulfonic acid (2R,3S,4R,5S,6S)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: NaH₂PO₂ / Raney nickel

2: sodium methoxide / methanol / 3 h

3: 1.93 g / triethylamine / CH₂Cl₂

4: 92 percent / sodium hydride / dimethylformamide / 0 - 20 °C

5: p-toluenesulfonic acid monohydrate / CH₂Cl₂; acetone / 0.05 h

6: sodium borohydride / methanol / 1 h

7: 895 mg / p-toluenesulfonic acid monohydrate / methanol / 2 h

8: 12 percent / pyridine / CH₂Cl₂ / 96 h

With pyridine; sodium tetrahydroborate; sodium hypophosphite; sodium methylate; sodium hydride; toluene-4-sulfonic acid; triethylamine; nickel; In methanol; dichloromethane; N,N-dimethyl-formamide; acetone; 1: Reduction / 2: Deacetylation / 3: Etherification / 4: Alkylation / 5: Hydrolysis / 6: Reduction / 7: detritylation / 8: Tosylation;
DOI:10.1016/S0040-4020(99)00327-0