D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate

Base Information

Chemical Name:D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate
CAS No.:228115-81-9
Molecular Formula:C₁₃H₁₆O₉
Molecular Weight:316.265
Hs Code.:

Synonyms:D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate

Suppliers and Price of D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate

Chemical Property:

PSA：114.43000
LogP:-0.89430

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate

There total 2 articles about D-glycero-L-manno-Heptonic acid, 2,6-anhydro-, .delta.-lactone, 3,4,7-triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3737-59-5
2,6-anhydro-D-glycero-L-manno-heptononitrile

: 108-24-7
acetic anhydride

: 228115-81-9
Acetic acid (1S,4R,6R,7S,8R)-8-acetoxy-6-acetoxymethyl-3-oxo-2,5-dioxa-bicyclo[2.2.2]oct-7-yl ester

Guidance literature:: 2,6-anhydro-D-glycero-L-manno-heptononitrile; With sodium hydroxide; In water; for 6h; Heating;

acetic anhydride; With pyridine;
DOI:10.1016/S0040-4020(99)00327-0

Reference yield:

: 228115-82-0
3,4,7-tri-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptonic acid

: 228115-81-9
Acetic acid (1S,4R,6R,7S,8R)-8-acetoxy-6-acetoxymethyl-3-oxo-2,5-dioxa-bicyclo[2.2.2]oct-7-yl ester

Guidance literature:: With sodium acetate; acetic anhydride; Heating;
DOI:10.1016/S0040-4020(99)00327-0

Reference yield:

: 228115-81-9
Acetic acid (1S,4R,6R,7S,8R)-8-acetoxy-6-acetoxymethyl-3-oxo-2,5-dioxa-bicyclo[2.2.2]oct-7-yl ester

: 2,6-anhydro-3,4-O-isopropylidene-7-thio-1-O-p-toluenesulfonyl-L-glycero-L-galacto-heptitol

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium aluminum hydride / tetrahydrofuran / 2 h / Heating

1.2: 21.2 g / pyridine

2.1: 33 percent / pyridine / 6 h

3.1: p-toluenesulfonic acid

4.1: 160 mg / lithium sulfide / dimethylformamide / 23 h / 20 - 80 °C

With pyridine; lithium aluminium tetrahydride; lithium sulfide; toluene-4-sulfonic acid; In tetrahydrofuran; N,N-dimethyl-formamide; 1.1: Reduction / 1.2: Acetylation / 2.1: Tosylation / 3.1: ketalization / 4.1: Substitution;
DOI:10.1016/S0040-4020(99)00327-0