1-benzyl-pseudouridine

Base Information

• Chemical Name: 1-benzyl-pseudouridine
• CAS No.: 1613530-22-5
• Molecular Formula: C₁₆H₁₈N₂O₆
• Molecular Weight: 334.329
• Mol file: 1613530-22-5.mol

Synonyms:1-benzyl-pseudouridine

Chemical Property of 1-benzyl-pseudouridine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-pseudouridine

There total 4 articles about 1-benzyl-pseudouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

C34H60N2O6Si3 (1613530-21-4) → 1-benzyl-pseudouridine (1613530-22-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃;

Reference yield: 51.0%

→ 1-benzyl-pseudouridine (1613530-22-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran;

Reference yield:

5-[(2S,3S,4R,5R)-3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione → 1-benzyl-pseudouridine (1613530-22-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,O-bis-(trimethylsilyl)-acetamide / dichloromethane / 4 h / 40 °C

1.2: 120 h / Reflux

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C

With N,O-bis-(trimethylsilyl)-acetamide; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;

upstream raw materials:

C₃₄H₆₀N₂O₆Si₃

pseudouridine

Refernces

• 1、 -. "ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF". Page/Page column 614. . Retrieved 2016/06/28.
• 2、 -. "MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF". Page/Page column 273. . Retrieved 2014/07/07.