Technology Process of N-benzyl-N-[1-(2-hydroxymethylphenyl)vinyl]-2-methoxybenzamide
There total 5 articles about N-benzyl-N-[1-(2-hydroxymethylphenyl)vinyl]-2-methoxybenzamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); sodium carbonate;
In
1,2-dimethoxyethane;
DOI:10.1055/s-0031-1290751
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium hexamethylsilazane / tetrahydrofuran / -78 °C
2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,2-dimethoxyethane
With
tetrakis(triphenylphosphine) palladium(0); potassium hexamethylsilazane; sodium carbonate;
In
tetrahydrofuran; 1,2-dimethoxyethane;
2: Suzuki-Miyaura cross coupling;
DOI:10.1055/s-0031-1290751
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydride / tetrahydrofuran
2: potassium hexamethylsilazane / tetrahydrofuran / -78 °C
3: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,2-dimethoxyethane
With
tetrakis(triphenylphosphine) palladium(0); potassium hexamethylsilazane; sodium hydride; sodium carbonate;
In
tetrahydrofuran; 1,2-dimethoxyethane;
3: Suzuki-Miyaura cross coupling;
DOI:10.1055/s-0031-1290751
