N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide

Base Information

Chemical Name:N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide
CAS No.:882999-17-9
Molecular Formula:C₂₅H₁₆Cl₂F₄N₂O₃S
Molecular Weight:571.379
Hs Code.:

Synonyms:N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide

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Technology Process of N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide

There total 1 articles about N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: (2E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]prop-2-enoic acid

: 287172-63-8
2,4,5-trifluorobenzenesulfonamide

: 882999-17-9
N-{(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-2,4,5-trifluorobenzenesulfonamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 22h;
DOI:10.1021/jm9005912