3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Base Information

Chemical Name:3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal
CAS No.:947594-95-8
Molecular Formula:C₂₆H₃₁ClN₂O₂S
Molecular Weight:471.063
Hs Code.:

Synonyms:3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Suppliers and Price of 3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

There total 5 articles about 3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 947594-94-7
3β-(4-methylphenyl)tropane-2β-N-4'-chlorophenacylcarboxamide ethylene ketal

: 947594-95-8
3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Guidance literature:: 3β-(4-methylphenyl)tropane-2β-N-4'-chlorophenacylcarboxamide ethylene ketal; With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -45 - 0 ℃;

With hydrogen sulfide; In dichloromethane; at 0 ℃; Further stages.;
DOI:10.1021/jm0703035

Reference yield:

: 947594-48-1
4-chlorophenacyl azide ethylene ketal

: 947594-95-8
3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Guidance literature:: Multi-step reaction with 3 steps

1.1: triphenylphosphine / tetrahydrofuran

1.2: 54 percent / water / tetrahydrofuran

2.1: 65 percent / 1-hydroxy-7-azabenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 25 °C

3.1: triflic anhydride; pyridine / CH₂Cl₂ / -45 - 0 °C

3.2: 47 percent / hydrogen sulfide / CH₂Cl₂ / 0 °C

With pyridine; 1-hydroxy-7-aza-benzotriazole; trifluoromethylsulfonic anhydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1.1: Staudinger reaction;
DOI:10.1021/jm0703035

Reference yield:

: 800401-76-7
4-chlorophenacylamine ethylene ketal

: 947594-95-8
3β-(4-methylphenyl)tropane-2β-N-4-chlorophenacylcarboxthioamide ethylene ketal

Guidance literature:: Multi-step reaction with 2 steps

1.1: 65 percent / 1-hydroxy-7-azabenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 25 °C

2.1: triflic anhydride; pyridine / CH₂Cl₂ / -45 - 0 °C

2.2: 47 percent / hydrogen sulfide / CH₂Cl₂ / 0 °C

With pyridine; 1-hydroxy-7-aza-benzotriazole; trifluoromethylsulfonic anhydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0703035