(6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone

Base Information

• Chemical Name: (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone
• CAS No.: 385390-30-7
• Molecular Formula: C₂₀H₁₈BrNO₅
• Molecular Weight: 432.271
• Mol file: 385390-30-7.mol

Synonyms:(6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone

Chemical Property of (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone

There total 15 articles about (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C22H26BrNO7 (1160948-81-1) → (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone (385390-30-7)

Guidance literature:

With sulfuric acid; acetic acid; In methanol; at 0 - 20 ℃;

DOI:10.1021/jo900311g

Reference yield:

C32H27BrNO9P (945594-73-0) → (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone (385390-30-7)

Guidance literature:

With Dimethylphenylsilane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1039/b706087d

Reference yield:

7-(6-bromo-2,3-dimethoxy-benzoyl)-6,7,8,9-tetrahydro-5H-1,3-dioxa-7-aza-cyclohepta[f]indene-6-carboxylic acid → (6-bromo-2,3-dimethoxy-phenyl)-(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-methanone (385390-30-7)

Guidance literature:

With pyridine; lead(IV) acetate; copper diacetate; In N,N-dimethyl-formamide; at 0 - 105 ℃;

DOI:10.1021/ol016795b

upstream raw materials:

C₃₂H₂₇BrNO₉P

C₂₀H₁₈BrNO₆

1,3-benzodioxole-5-acetic acid

3,4-methylenedioxyphenylacetyl chloride

Downstream raw materials:

lennoxamine

(5,6-dihydro-1,3-dioxa-7-aza-cyclohepta[f]inden-7-yl)-(2,3-dimethoxy-phenyl)-methanone