2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid

Base Information

• Chemical Name: 2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid
• CAS No.: 499789-75-2
• Molecular Formula: C₂₂H₂₇NO₅
• Molecular Weight: 385.46
• Mol file: 499789-75-2.mol

Synonyms:2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid

Chemical Property of 2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid

There total 1 articles about 2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-bromoethoxy)-4-isopropylbenzene (467236-24-4) + methyl 2-[(2-oxo-1,2-dihydro-4-pyridinyl)methyl]tetrahydro-2-furancarboxylate (499789-44-5) → 2-({2-[2-(4-isopropylphenoxy)ethoxy]-4-pyridyl}methyl)-tetrahydrofuran-2-furancarboxylic acid (499787-83-6) + 2-({1-[2-(4-isopropylphenoxy)ethyl]-2-oxo-1,2-dihydro-4-pyridinyl}-methyl)tetrahydrofuran-2-furancarboxylic acid (499789-75-2)

Guidance literature:

1-(2-bromoethoxy)-4-isopropylbenzene; methyl 2-[(2-oxo-1,2-dihydro-4-pyridinyl)methyl]tetrahydro-2-furancarboxylate; With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 70 ℃; for 18h;

In tetrahydrofuran; ethanol; water; at 20 ℃; for 14h;

With hydrogenchloride; In water; ethyl acetate; pH=4;

upstream raw materials:

1-(2-bromoethoxy)-4-isopropylbenzene

methyl 2-[(2-oxo-1,2-dihydro-4-pyridinyl)methyl]tetrahydro-2-furancarboxylate