Technology Process of Pentonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)
There total 10 articles about Pentonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: LHMDS, I2 / tetrahydrofuran / 2 h / -46 - -23 °C
2: TBAF / tetrahydrofuran / 1 h / -46 - -15 °C
3: HCO2H / 10 h / Ambient temperature
With
formic acid; tetrabutyl ammonium fluoride; iodine; lithium hexamethyldisilazane;
In
tetrahydrofuran;
DOI:10.1016/S0040-4020(99)00367-1
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / H2 / Pd(OH)2/C / methanol / 4 h / 50 °C
2: HCO2H / 12 h / Ambient temperature
With
formic acid; hydrogen;
palladium dihydroxide;
In
methanol;
DOI:10.1016/S0040-4020(99)00367-1
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 91 percent / imidazole / dimethylformamide / 0 deg C to rt
2: LHMDS, I2 / tetrahydrofuran / 1.5 h / -46 °C
3: 22.3 mg / TBAF / tetrahydrofuran / 1 h / -46 - -15 °C
4: 96 percent / H2 / Pd(OH)2/C / methanol / 4 h / 50 °C
5: HCO2H / 12 h / Ambient temperature
With
1H-imidazole; formic acid; tetrabutyl ammonium fluoride; hydrogen; iodine; lithium hexamethyldisilazane;
palladium dihydroxide;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(99)00367-1
