methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Base Information

Chemical Name:methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate
CAS No.:306972-09-8
Molecular Formula:C₂₅H₂₃NO₅S
Molecular Weight:449.527
Hs Code.:

Synonyms:methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Suppliers and Price of methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

There total 4 articles about methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 306972-07-6
methyl (2S,3S)-3,4-bismethanosulfonyloxy-2-(9'-phenylfluoren-9'-ylamino)butyrate

: 306972-09-8
methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Guidance literature:: With 2,4,6-trimethyl-pyridine; lithium perchlorate; In 1,4-dioxane; at 70 ℃; for 8h;
DOI:10.1021/jo000732+

Reference yield:

: 306972-07-6
methyl (2S,3S)-3,4-bismethanosulfonyloxy-2-(9'-phenylfluoren-9'-ylamino)butyrate

: (2S,3R)-3-Methanesulfonyloxy-1-(9-phenyl-9H-fluoren-9-yl)-azetidine-2-carboxylic acid methyl ester

: 306972-09-8
methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1021/jo000732+

Reference yield:

: 144331-15-7
(2S,3S)-Dimethyl N-(9'-phenylfluoren-9'-yl)-3-hydroxyaspartate

: 306972-09-8
methyl (2S,3R)-3-methanosulfonyloxymethyl-1-(9'-phenylfluoren-9'-yl)aziridine carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: BH₃*SMe₂ / tetrahydrofuran / 0.5 h / 20 °C

1.2: 88 percent / NaBH₄ / tetrahydrofuran / 46 h / 20 °C

2.1: 97 percent / DMAP; pyridine / CH₂Cl₂ / 12 h / 20 °C

3.1: Et₃N / dimethylformamide / 80 °C

With pyridine; dmap; dimethylsulfide borane complex; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1.1: Addition / 1.2: Reduction / 2.1: mesylation / 3.1: Cyclization;
DOI:10.1021/jo000732+