methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Base Information

Chemical Name:methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal
CAS No.:945224-39-5
Molecular Formula:C₂₉H₅₀O₇S₂Si
Molecular Weight:602.929
Hs Code.:

Synonyms:methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Suppliers and Price of methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

There total 6 articles about methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 945224-38-4
C₂₀H₃₀O₄S₂

: 150811-50-0
(E)-((2-((tert-butyldimethylsilyl)oxy)-1-methoxyvinyl)oxy)trimethylsilane

: 945224-39-5
methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Guidance literature:: With magnesium bromide; In dichloromethane; toluene; at -78 - 20 ℃; for 6h;
DOI:10.1002/chem.200700141

Reference yield:

: 945224-31-7
3-O-benzyl-4,5-O-isopropylidene-D-xylose di(ethylthio)acetal

: 945224-39-5
methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / 4-dimethylaminopyridine / CH₂Cl₂ / 1 h / 0 °C

2: 100 percent / aq. acetic acid / 3 h / 50 °C

3: 82 percent / sodium periodate / H₂O; tetrahydrofuran / 2 h / 20 °C

4: 85 percent / MgBr₂*OEt₂ / toluene; CH₂Cl₂ / 6 h / -78 - 20 °C

With dmap; sodium periodate; acetic acid; magnesium bromide; In tetrahydrofuran; dichloromethane; water; toluene; 4: Mukaiyama aldol reaction;
DOI:10.1002/chem.200700141

Reference yield:

: 945224-30-6
3-O-benzyl-D-xylose di(ethylthio)acetal

: 945224-39-5
methyl 2-O-pivaloyl-3-O-benzyl-5-O-tert-butyldimethylsilyl-D-glucuronate di(ethylthio)acetal

Guidance literature:: Multi-step reaction with 5 steps

1: 93 percent / pTsOH / 12 h / 20 °C

2: 100 percent / 4-dimethylaminopyridine / CH₂Cl₂ / 1 h / 0 °C

3: 100 percent / aq. acetic acid / 3 h / 50 °C

4: 82 percent / sodium periodate / H₂O; tetrahydrofuran / 2 h / 20 °C

5: 85 percent / MgBr₂*OEt₂ / toluene; CH₂Cl₂ / 6 h / -78 - 20 °C

With dmap; sodium periodate; toluene-4-sulfonic acid; acetic acid; magnesium bromide; In tetrahydrofuran; dichloromethane; water; toluene; 5: Mukaiyama aldol reaction;
DOI:10.1002/chem.200700141