tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate

Base Information

• Chemical Name: tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate
• CAS No.: 1182206-92-3
• Molecular Formula: C₂₄H₃₁N₇O₆
• Molecular Weight: 513.553

Synonyms:tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate

Chemical Property of tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate

There total 1 articles about tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

tert-butyl N6-[(benzyloxy)carbonyl]-8-[(1-(2-ethoxy-2-oxoethyl)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}hydrazino)methyl]adenine-9-acetate (1182206-80-9) → tert-butyl N6-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate (1182206-92-3)

Guidance literature:

With piperidine; In N,N-dimethyl-formamide; at 0 ℃; Inert atmosphere;

DOI:10.1002/hlca.200900047

Reference yield:

tert-butyl N6-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate (1182206-92-3) + N6-[(benzyloxy)carbonyl]-8-[(1-(2-ethoxy-2-oxoethyl)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}hydrazino)methyl]adenine-9-acetic acide (1182206-93-4) → (6-{[(benzyloxy)carbonyl]amino}-8-{[2-{[6-{[(benzyloxy)carbonyl]amino}-8-({1-(2-ethoxy-2-oxoethyl)-2-[(9H-fluoren-9-ylmethoxy)carbonyl]hydrazinyl}methyl)-9H-purin-9-yl]acetyl}-1-(2-ethoxy-2-oxoethyl)hydrazinyl]methyl}-9H-purin-9-yl)acetic acid (1328885-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: triethylsilane; trifluoroacetic acid / dichloromethane / 48 h / 20 °C / Inert atmosphere

With triethylsilane; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/hlca.201100124

upstream raw materials:

tert-butyl N₆-[(benzyloxy)carbonyl]-8-[(1-(2-ethoxy-2-oxoethyl)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}hydrazino)methyl]adenine-9-acetate

Downstream raw materials:

(6-{[(benzyloxy)carbonyl]amino}-8-{[2-{[6-{[(benzyloxy)carbonyl]amino}-8-({1-(2-ethoxy-2-oxoethyl)-2-[(9H-fluoren-9-ylmethoxy)carbonyl]hydrazinyl}methyl)-9H-purin-9-yl]acetyl}-1-(2-ethoxy-2-oxoethyl)hydrazinyl]methyl}-9H-purin-9-yl)acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1182206-92-3 tert-butyl N₆-[(benzyloxy)carbonyl]-8-{[1-(2-ethoxy-2-oxoethyl)hydrazino]methyl}adenine-9-acetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send