2,2,3,3-Tetrafluorocyclobutanol

Base Information

Chemical Name:2,2,3,3-Tetrafluorocyclobutanol
CAS No.:374-32-3
Molecular Formula:C4H4 F4 O
Molecular Weight:144.069
Hs Code.:2906199090
DSSTox Substance ID:DTXSID60380214
Mol file:374-32-3.mol

Synonyms:2,2,3,3-TETRAFLUOROCYCLOBUTANOL;374-32-3;2,2,3,3-tetrafluorocyclobutan-1-ol;Cyclobutanol, 2,2,3,3-tetrafluoro-;SCHEMBL1766309;DTXSID60380214;MFCD00190085;AKOS006228767;AS-77925;FT-0609079;EN300-7606134

Suppliers and Price of 2,2,3,3-Tetrafluorocyclobutanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2,3,3-Tetrafluorocyclobutanol
500mg
$ 220.00

SynQuest Laboratories
2,2,3,3-Tetrafluorocyclobutanol 97%
1 g
$ 95.00

SynQuest Laboratories
2,2,3,3-Tetrafluorocyclobutanol 97%
5 g
$ 380.00

CHESS?
SG000594:2,2,3,3-Tetrafluorocyclobutanol 95
5 g
$ 300.00

American Custom Chemicals Corporation
2,2,3,3-TETRAFLUOROCYCLOBUTANOL 95.00%
5G
$ 1189.65

American Custom Chemicals Corporation
2,2,3,3-TETRAFLUOROCYCLOBUTANOL 95.00%
1G
$ 687.23

Alfa Aesar
2,2,3,3-Tetrafluorocyclobutanol, 95%
5g
$ 527.00

Alfa Aesar
2,2,3,3-Tetrafluorocyclobutanol, 95%
1g
$ 127.00

Total 16 raw suppliers

Chemical Property of 2,2,3,3-Tetrafluorocyclobutanol

Chemical Property:

Vapor Pressure:19.8mmHg at 25°C
Refractive Index:1.368
Boiling Point:155-157°C
Flash Point:155-157°C
PSA：20.23000
Density:1,414 g/cm3
LogP:1.02160
Water Solubility.:Not miscible or difficult to mix in water.
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:144.01982740
Heavy Atom Count:9
Complexity:133

Purity/Quality:

98%Min ^*data from raw suppliers

2,2,3,3-Tetrafluorocyclobutanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C1(F)F)(F)F)O
Uses 2,2,3,3-Tetrafluorocyclobutanol is used as a pharmaceutical intermediate.

Technology Process of 2,2,3,3-Tetrafluorocyclobutanol

There total 2 articles about 2,2,3,3-Tetrafluorocyclobutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135947-13-6
2,2,3,3-tetrafluorocyclobutyl isopropyl ether

: 374-32-3
2,2,3,3-tetrafluorocyclobutanol

Guidance literature:: With conc. sulphuric acid;

Reference yield:

: 374-32-3
2,2,3,3-tetrafluorocyclobutanol

Guidance literature:

Reference yield: 70.0%

: 2-(methylsulfonyl)-5-((1r,4r)-4-(piperidin-4-yloxy)cyclohexyloxy)pyrazine hydrochloride

: 374-32-3
2,2,3,3-tetrafluorocyclobutanol

: 530-62-1
1,1'-carbonyldiimidazole

: 2,2,3,3-tetrafluorocyclobutyl 4-((1r,4r)-4-(5-(methylsulfonyl)pyrazin-2-yloxy)cyclohexyloxy)piperidine-1-carboxylate

Guidance literature:: 2,2,3,3-tetrafluorocyclobutanol; 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 1.5h;

2-(methylsulfonyl)-5-((1r,4r)-4-(piperidin-4-yloxy)cyclohexyloxy)pyrazine hydrochloride; With triethylamine; In tetrahydrofuran; at 80 ℃;