1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea

Base Information

• Chemical Name: 1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea
• CAS No.: 950919-63-8
• Molecular Formula: C₂₂H₂₇N₃O₂S
• Molecular Weight: 397.541
• Mol file: 950919-63-8.mol

Synonyms:1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea

Chemical Property of 1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea

There total 1 articles about 1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-amino-1-isopropyl-7-methyl-4-azatricyclo[5.2.2.0(2,6)]undec-8-ene-3,5-dione (4098-80-0) + Benzyl isothiocyanate (622-78-6) → 1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea (950919-63-8)

Guidance literature:

In acetonitrile; for 6h; Reflux;

DOI:10.1016/j.ejmech.2009.08.013

Reference yield: 62.0%

1,4-dibromo-butane (110-52-1) + 1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea (950919-63-8) → 1-isopropyl-7-methyl-4-{2-[(Z)-benzylimino]-1,3-thiazepan-3-yl}-4-azatricyclo [5.2.2.0(2,6)]undec-8-ene-3,5-dione

Guidance literature:

1-(4-benzylphenyl)-3-(1-isopropyl-7-methyl-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-8-en-4-yl)-thiourea; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃;

1,4-dibromo-butane; In N,N-dimethyl-formamide; mineral oil; for 6h;

DOI:10.1016/j.ejmech.2009.08.013

upstream raw materials:

4-amino-1-isopropyl-7-methyl-4-azatricyclo[5.2.2.0(2,6)]undec-8-ene-3,5-dione

Benzyl isothiocyanate