Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane

Base Information

• Chemical Name: Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane
• CAS No.: 220092-49-9
• Molecular Formula: C₄₀H₄₈O₅Si
• Molecular Weight: 636.904

Synonyms:Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane

Chemical Property of Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane

There total 2 articles about Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

(2S,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-2-((E)-1-methyl-2-trimethylsilanyl-vinyl)-tetrahydro-pyran-2-ol (220092-48-8) → Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane (220092-49-9)

Guidance literature:

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; acetonitrile; at -40 ℃; for 0.25h;

DOI:10.1021/jo9815305

Reference yield:

((1E)-2-iodoprop-1-en-1-yl)(trimethyl)silane (148933-44-2) → Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane (220092-49-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) t-BuLi / 1.) THF, -78 deg C, 30 min, 2.) THF, -78 deg C, 1 h

2: 49 percent / Et₃SiH, BF₃*Et₂O / acetonitrile; CH₂Cl₂ / 0.25 h / -40 °C

With triethylsilane; boron trifluoride diethyl etherate; tert.-butyl lithium; In dichloromethane; acetonitrile;

DOI:10.1021/jo9815305

Reference yield: 95.0%

Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane (220092-49-9) → (E)-2-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-iodoprop-1-ene

Guidance literature:

With N-iodo-succinimide; In tetrahydrofuran; for 24h;

DOI:10.1021/jo9815305

upstream raw materials:

(2S,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-2-((E)-1-methyl-2-trimethylsilanyl-vinyl)-tetrahydro-pyran-2-ol

((1E)-2-iodoprop-1-en-1-yl)(trimethyl)silane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220092-49-9 Trimethyl-[(E)-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-silane

Send

Send

Metric Ton KG G Pound L ML

Send

Send