N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Base Information

Chemical Name:N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester
CAS No.:148843-40-7
Molecular Formula:C₃₁H₃₃N₃O₅
Molecular Weight:527.62
Hs Code.:

Synonyms:N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Suppliers and Price of N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

There total 4 articles about N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 22839-16-3
L-tryptophan benzyl ester hydrochloride

: 151927-75-2
2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoic acid

: 148843-40-7
N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Guidance literature:: With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; 1.) 0 deg C, 1 h, 2.) 20 deg C, 48 h;
DOI:10.1021/jm00012a011

Reference yield:

: 759-36-4
diethyl isopropylmalonate

: 148843-40-7
N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: KOH / ethanol

2: HOBT, DCC / CH₂Cl₂ / 1.) 5 deg C, 1 h, 2.) 20 deg C, 68 h

3: KOH, water / ethanol / 18 h

4: 69 percent / DCC, HOBT-H₂O, iPr₂NEt / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 20 deg C, 48 h

With potassium hydroxide; water; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00012a011

Reference yield:

: potassium 2-(ethoxycarbonyl)-3-methylbutanoate

: 148843-40-7
N-<2-<<(phenylmethoxy)amino>carbonyl>-3-methylbutanoyl>-L-tryptophan phenyl methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: HOBT, DCC / CH₂Cl₂ / 1.) 5 deg C, 1 h, 2.) 20 deg C, 68 h

2: KOH, water / ethanol / 18 h

3: 69 percent / DCC, HOBT-H₂O, iPr₂NEt / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 20 deg C, 48 h

With potassium hydroxide; water; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00012a011