(R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

Base Information

Chemical Name:(R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide
CAS No.:890415-64-2
Molecular Formula:C₂₆H₂₅N₂OP
Molecular Weight:412.471
Hs Code.:

Synonyms:(R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

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Chemical Property of (R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

Chemical Property:

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Technology Process of (R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

There total 3 articles about (R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 426225-26-5
((R)-1-Phenyl-ethyl)-[1-pyridin-4-yl-meth-(E)-ylidene]-amine

: 4559-70-0
Diphenylphosphine oxide

: 890415-64-2
(R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

: (R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(R)-methyldiphenylphosphine oxide

Guidance literature:: In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.tet.2006.02.048

Reference yield:

: 872-85-5
pyridine-4-carbaldehyde

: 890415-64-2
(R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 48 h / 20 °C

2: 2.02 g / CH₂Cl₂ / 24 h / 20 °C

In dichloromethane;
DOI:10.1016/j.tet.2006.02.048

Reference yield:

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 890415-64-2
(R)-(+)-1-[N-(α-methylbenzylamino)]-1-(4-pyridyl)-(S)-methyldiphenylphosphine oxide

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 48 h / 20 °C

2: 2.02 g / CH₂Cl₂ / 24 h / 20 °C

In dichloromethane;
DOI:10.1016/j.tet.2006.02.048