Technology Process of ethyl 5-(3-aminophenyl)-2-phenylpentanoate
There total 4 articles about ethyl 5-(3-aminophenyl)-2-phenylpentanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrazine;
In
methanol; ethanol; water;
at 20 ℃;
Inert atmosphere;
Reflux;
DOI:10.1021/jm101182s
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 2.25 h / -15 °C / Inert atmosphere
1.2: 3.83 h / -78 - 20 °C / Inert atmosphere
2.1: hydrazine / methanol; ethanol; water / 20 °C / Inert atmosphere; Reflux
With
n-butyllithium; diisopropylamine; hydrazine;
In
tetrahydrofuran; methanol; ethanol; water;
DOI:10.1021/jm101182s
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuric acid / 1.5 h / Reflux
2.1: lithium borohydride; 1-Decene / tetrahydrofuran / 18 h / 20 °C / Inert atmosphere
3.1: 1H-imidazole; iodine; triphenylphosphine / toluene / 3 h / 20 °C / Inert atmosphere
4.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 2.25 h / -15 °C / Inert atmosphere
4.2: 3.83 h / -78 - 20 °C / Inert atmosphere
5.1: hydrazine / methanol; ethanol; water / 20 °C / Inert atmosphere; Reflux
With
1H-imidazole; lithium borohydride; n-butyllithium; 1-Decene; sulfuric acid; iodine; diisopropylamine; triphenylphosphine; hydrazine;
In
tetrahydrofuran; methanol; ethanol; water; toluene;
DOI:10.1021/jm101182s